Melanoma now detectable by skin odor
Responsible for more than 75 percent of skin cancer deaths, melanoma is a cancer of the skin, which affects the melanocytes (pigment carrying cells of the body). A new study now suggests that this dangerous cancer may be easily detectable - by odors from skin cells.
The study, carried out by a team of researchers from the Monell Center revealed two new ways to help early detection of skin cancer- by odors emitted by human skin, and by using a nanotechnology-based sensor that could differentiate between normal skin cells and melanoma skin cells.
Early methods of detection of this deadly form of skin cancer relied on physical examination only; but this new study is about to change it all.
The researchers took into consideration the fact that human skin produces a number of airborne chemical molecules, also known as volatile organic compounds (VOCs), many of which emit odor too, and put it to use as an early melanoma detection tool.
"There is a potential wealth of information waiting to be extracted from examination of VOCs associated with various diseases, including cancers, genetic disorders, and viral or bacterial infections," senior author George Preti, PhD and an organic chemist at Monell, noted.
For this study, the researchers made use of sophisticated analytical and sampling techniques that helped detect VOCs emitted from melanoma skin cells at different levels of progression of the disease. They also sampled VOCs emitted from normal skin cells by using an absorbent device. Analysis of these VOCs was done using mass spectrometry and gas chromatography techniques.
To translate the results obtained from the VOC analysis into a diagnostic analysis, a reliable and portable sensor would be required, to which, the researchers used a nano-sensor.
The nano-sensor was made up of two nano-sized tubes that were coated with strands of DNA. The use of DNA as a sensor could be clarified by the fact that DNA tend to act as a wonderful sensor, which makes identification of the target easy. The results so obtained revealed a stunning fact- human skin cells emit odor different from that of melanoma skin cells; a new early diagnostic tool which may help cut down death rates due to melanoma considerably.
"This study demonstrates the usefulness of examining VOCs from diseases for rapid and noninvasive diagnostic purposes," Preti said. "The methodology should also allow us to differentiate stages of the disease process."
The study is now published in the Journal of Chromatography B.
The Good News On Cancer: FDA Approves Immunotherapy Cancer Drugs, Is This The Answer To Cancer?
Considering that there's no known cure to cancer, how can the FDA's approval of the alleged cancer drugs be essential in the field of medicine? Is this the final answer to one of the long dreaded disease of the world? Is Immunotherapy the key to cancer? Here's what health professionals have to say
Artificial Intelligence Used To Identify Skin Cancer Effectively
Computers are taking over more tasks done by humans. Artificial intelligence can be used to identify skin cancer effectively now.
Researchers Say; That Having A Tattoo Could Help To Reduce Skin Cancer
For most people today, getting inked is an acceptable, relatively a "into" activity. According to a Harris poll, roughly one in four to five American adults can now have at least one tattoo.
Skin Cancer Isn’t Scaring People Who Use Indoor Tanning
Skin cancer could be caused by tanning bads, but skin cancer isn't scaring people who use indoor tanning.
Melanoma Treatment: New Drug Could Stop Spread Disease By 90%
A newly-developed drug which contains small-molecule chemical compound could be the best melanoma treatment. It can effectively stop a gene activity to produce proteins in melanoma tumors, stopping the spread of the disease by 90 percent.
New Technology Helps Detect Early Skin Cancer Stage
Researchers from the Rockefeller University in the US were able to develop an automated technology which combines digital analysis and machine learning to detect melanoma. This technology could, researchers say, could "save lives, and avoid unnecessary biopsies."
MORE IN ITECHPOST
5 Highly Anticipated Techs Still Coming In 2017
The upcoming iPhone 8 leads a formidable cast of highly anticipated devices that are yet to be launched this 2017.
'Tokyo Ghoul' Season 3 Delayed By Its Live-Action Movie? Ken Kenaki Returns With Another Identity?
"Tokyo Ghoul" season 3's release is delayed and there are countless speculations as to why it is being pushed back. Reports claim that the show is to give way to "One Punch Man" and "My Hero Acdemia" but new rumors say that it's lack of materials and storyline as well as its live-action movie are causing the delay.
'Ultra Street Fighter 2: The Final Challengers' Earns Glowing Reviews
Following the release of "Ultra Street Fight 2: The Final Challengers," reviews flock to sing praises and applause. Check out the full details here!