The Final Answer For HIV? How Effective Is Sofosbuvir/Ledispasvir For People With HIV And HCV?
In a couple of days, the annual celebration of World AIDS day will once again be celebrated. It was in line with this fact that UN has called for urgent series of actions which is necessary in order to help and protect HIV patients across the globe.
In the recently concluded 2016 AASLD Liver meeting this month, the pooled analysis has shown that the sofosbuvir/ledipasvir also known as Harvoni co-formulation which is widely used in real-world clinical practice has produced good sustained virological response rates , which is similar to those seen in clinical trials for HIV-positive people with hepatitis C co-infection.
Sofosbuvir/Ledispasvir Being Used For HIV Patients, How Effective Was It?
It was found that HIV-positive people who have co infection with hepatitis C virus (HCV) experience more rapid liver disease progression on average and did not respond as well as HIV-negative people to interferon-based hepatitis C treatment. As per Aids Map, Susanna Naggie of Duke University and colleagues was found to have compared the efficacy of the sofosbuvir/ledipasvir single tablet regimen for people with HIV/HCV co-infection with HCV genotype 1 in clinical trials against its effectiveness in real-world cohorts.
On the other hand, according to Info Hep, it was found that new and direct-acting antivirals (DAAs) used in interferon-free regimens have made treatment simpler, better tolerated and much more effective. Clinical trials showed that DAAs work as well for HIV-positive as for HIV-negative people with hepatitis C. However, scientists have highly emphasized the fact that despite the study findings, they still need to be aware of potential drug-drug interactions with antiretrovirals.
Ultimately, the researchers of the study concludes that sustained virological response rates were high across all populations including populations with traditional negative predictors such as black race, cirrhosis, and treatment-experienced patients. Accordingly, experts have added that the results have coincided with the recent EASL guidelines and AASLD/IDSA guidelines, which recommend sofosbuvir/ledipasvir for people with HIV/HCV co-infection.
University Study Says 'Pokemon GO' Encourages Physical Activity
A University conducted a study to determine if "Pokemon GO" helps gamers get some exercise.
Elon Musk Is Working On A Consensual Telepathy; Latest Details Inside
Elon Musk has confirmed that Neuralink is real and that he is serious about the technology. The firm will soon develop a “neural lace” technology that would involve implanting tiny brain electrodes.
HIV, The Next Target Of Trump Administration
As continuous efforts to eradicate HIV are taking place, why does the Trump administration wanted to halt the treatment that has been started by the previous government? What’s the truth behind claims that if the current US President would push this through, it will kill thousands? Find out what authorities have to say
How Do We Reduce HIV Risk? Here Are Experts' Tips
With the continuous efforts to eradicate one of the world's long dreaded disease, can we really do certain precautionary measures to prevent the risk of HIV? What are the necessary steps to prevent transmission of the disease? Find out what experts have to say
HIV Vaccine Cures Five Patients For Seven Months
New AIDS vaccine developed in Spain have reportedly cured 5 patients, helping them remain virus-free for seven months after taking the treatment. In the study, the treatment allowed the patients to stop taking regular antiretroviral (ARV) drugs to suppress HIV symptoms.
Nanotechnology For HIV: New Technique Shows Promising Results In HIV Treatment
With continuous efforts to eradicate HIV being one of the world's long dreaded disease, how essential does nanotechnology's role can be? What's the truth behind claims that this new technique offers a new hope as it has induced positive results in HIV treatment? Could it be the answer to the disease? Find out what experts have to say
MORE IN ITECHPOST
Biochip Advances Enable Next-Generation Sequencing Technologies
Biochips are essentially tiny laboratories designed to function inside living organisms, and they are driving next-generation DNA sequencing technologies. This powerful combination is capable of solving unique and important biological problems, such as single-cell, rare-cell or rare-molecule analysis, which next-generation sequencing can't do on its own.
Stanford Researchers Teach Robots what Humans Want
Told to optimize for speed while racing down a track in a computer game, a car pushes the pedal to the metal ... and proceeds to spin in a tight little circle. Nothing in the instructions told the car to drive straight, and so it improvised.