Promising news about a brain cancer treatment is now sparking hope in cancer patients as news of its ability in wiping out cancer has proven to be true and successful. The new form of therapy used in battling tumors is proven to be effective and more successful in blood cancers.
Immunotherapy, specifically the Chimeric Antigen Receptor T cells or CAR-T therapy has been reported to have helped a patient with advanced brain cancer. This was cited in a research led by Dr. Benham Badie from the City of Hope Beckman Research Institute and Medical Centre and was published in the New England Journal of Medicine, Time reports.
As per Business Wire, the 50-year-old patient who had recurrent Multifocal Glioblastoma had undergone phase I clinical trial after not getting good results from resection, radiation and Temozolomide. The process involved him being infused with multiple doses that were well tolerated.
The reengineered CAR-T cells were directly injected into the tumor sites and ventricles where the spinal fluid was created. This helped deliver it to the patient's brain and spinal cord where the metastatic tumor can be found. After 7 and a half months of CAR-T therapy, regression was seen in both brain and spinal tumors. There was also an increase of immune cells in the cerebrospinal fluid.
"I believe these recent results show we have a potential breakthrough treatment that may have a remarkable impact on patients with malignant brain tumors," Badie said.
Lead author and scientist Christine Brown also states that the most exciting part of the study is that it proves that better treatment is attainable. The recent brain cancer treatment trial and study serves as a promising therapy as it will now be possible to preserve patients' neurological function while minimizing toxic effects from other treatments.
They believe that the successful brain cancer treatment can still be studied and developed further to create targeted immunotherapy options for cancers that are difficult to treat.