Tuberculosis Cure: Parasite Protein Could Be New Treatment
Parasite proteins plays a role in new tuberculosis cure. A study reveals that proteins produced by parasites could stimulate a molecular activity which can help fight tuberculosis. Researchers suggest host-directed tuberculosis therapies involving these proteins.
Tuberculosis is an infectious disease caused by the bacteria called mycobacterium tuberculosis. In most cases, it affects the lungs however, it can also infect other parts of the body. Some common symptoms of tuberculosis include cough with blood-containing sputum, weight loss, fever and night sweats.
Tuberculosis is thought to affect about one third of the world population. In 2014, there were 9.6 million cases of active tuberculosis resulting to less than 2 million deaths. Still, the statistics continue to increase each year.
Proteins from parasites which causes toxoplasmosis can help fight mycobacteria. A study published in PLOS Pathogens reveals that these proteins could be used in a new potential host-directed therapy for tuberculosis. Host-directed therapies are those which involve targeting the processes which help the bacteria survive rather than the bacteria itself.
Researchers at Hanyang University in South Korea tested the new tuberculosis cure in mycobacteria-infected mice. They were treated using mycobacteria-infected mice to observe the activity of GRA7 proteins. GRA7 are proteins produced by parasites after the host cells are infected.
They found out that a host protein, PKC, is important to the interaction between GRA7 and ASC or PLD1. This contribute to the antimicrobial defense against mycobacterium tuberculosis. "Taken together, these results underscore a previously unrecognized role of GRA7 in modulating antimicrobial host defense mechanism during mycobacterial infection," the researchers said on the study.
The study gives insight to the development of new potential tuberculosis cure using GRA7-based host-directed therapies, cited Science Daily. Common treatments to tuberculosis include use of antibiotics to kill the bacteria, however, some antibiotics become ineffective due to the unusual structure of the mycobacteria. More research is needed as the study was conducted on mice and human cells and not actual tuberculosis patients.
Mysterious Cases Of Amnesia Baffle Researchers
Sudden onset of amnesia in 14 patients with no clear cause baffles scientists. The only link among the patients is drug use. More research is needed to prove the connection of substance abuse to amnesia.
Many Diseases Linked To Mitochondrial Dysfunction
Researchers found a potential way to battle diseases caused by mitochondrial dysfunction through genetic intervention, using the so-called 'back-up' systems from lower animals.
How the Shape Of The Brain Can Influence Your Personality
Study reveals the shape of the brain is linked to five major personality traits including neuroticism, openness, extraversion, agreeableness, and conscientiousness.
BPaMZ And BPaL: These Two New Drug Therapies Might Cure All Forms Of Tuberculosis
Considering the adverse impacts brought by tuberculosis, is there still hope for the infectious bacterial disease? With the discovery of these two new drug therapies, what’s the truth behind claims that the answer for tuberculosis has finally arrived? Find out what health professionals have to say
Multi-Drug Resistant Tuberculosis Is On The Rise
There is more bad news regarding multi-drug resistant tuberculosis. A new study found that strains of tuberculosis that bypass most of the drugs that are usually used to treat bacterial infection have been spreading in South Africa, which already has a high tuberculosis infection rate. Health authorities are highly concerned of the extensively drug-resistant tuberculosis because of the way tuberculosis spreads.
Ohio's Hospital Neonatal Unit Potentially Exposed To Tuberculosis Bacteria
A patient recently diagnosed with tuberculosis reportedly visited Ohio's Hospital Neonatal Unit, prompting health officials to test all possibly exposed individuals, including infants. A tuberculosis case is rare in the US, and poses low risk to the public but could prove lethal to young children.
MORE IN ITECHPOST
The Role of Technology in Education in 2019
2019 is proving to be another great year for trends in educational technology. There are many upcoming trends that seem to have a bearing on the future of the sector with respect to technology.
New Retroreflective Material Could be Used in Nighttime Color-Changing Road Signs
BUFFALO, N.Y. -- A thin film that reflects light in intriguing ways could be used to make road signs that shine brightly and change color at night, according to a study that will be published on Aug. 9 in Science Advances.
Top 5 Video Games to Play for a Truly Unique First Date
Video games have a way of taking us outside of ourselves and live in a fantasy world. It's even better when you're playing a game with someone special!