Parkinson's Disease: Researchers Discover Genetic Switch
Parkinson’s disease is a disease of the nervous system, affecting middle-aged and elderly people. Researchers discovered that a gene called ATF4 could possibly act as a switch of genes that could control mitochondrial metabolism for neuron health. Dr Miguel Martins, lead researcher explained that when the expression of ATF4 is reduced in flies, expression of these mitochondrial genes drops. This drop results in dramatic locomotor defects, decreased lifespan, and dysfunctional mitochondria in the brain.
In addition to this when these mitochondrial genes were over exposed, mitochondrial function was restored, and neuron loss was avoided. Researchers have singled out new therapeutic targets that could prevent neuron loss. By determining the gene networks that organize this process.
Parkinson’s disease has several forms, some of which are called PINK1 and PARKIN. These are assisting in mitochondrial quality control. Fruit flies with alterations in these genes accrue abnormal mitochondria and exhibit Parkinson's-like changes, including loss of neurons.
The researchers used mutant flies with PINK1 and PARKIN to investigate other critical Parkinson's genes. They also used bioinformatics approach discovering that the ATF4 gene is an important aspect. According to the Meical News Today, Dr. Martin said that contemplating on these genes and their role in the human neurons could surpass creations of possible delays or prevention of the neuronal loss seen in Parkinson's disease.
The research results of the University of Leicester team, discovered various genes that take care of neurons in Parkinson's disease. This has opened potential creation of effective treatment alternative. According to the Science Daily, PINK1 and PARKIN, affect how mitochondria break down amino acids to generate nucleotides. They are in charge of the metabolism of these molecules generates the energy that cells need to live. The researchers believe that they have found several new ways that could potentially cure Parkinson’s disease.
Deep Brain Stimulation Shows Potential In Anorexia Therapy
Considering the continuous efforts to spread awareness to the adverse effects and the nature of Anorexia, have scientists just found the answer to the said medical condition? What's the truth behind claims that deep brain stimulation is allegedly showing promising results in anorexia therapy? Here's what experts have to say
Blood Test: An Early Detection Agent For Parkinson’s Disease, New Study Claims
Just as you thought Parkinson’s disease was undetectable, what’s the truth behind claims that a simple blood test can determine if you are at high risk for Parkinson’s? What component is there in our blood that it can be used to predict the disease? Here’s what health professionals have to say
Iron Overload In Babies May Lead To Parkinson's Disease
Recent studies have comfirmed that iron overload in childhood may play a role in the development of Parkinson's disease. The discovery is important in developing a test that can measure potential for the disease as early as possible, and also to make parents aware of the effects of too much iron in their children.
Hope For Multiple Sclerosis: Toxic Brain Cells Shed Light On Multiple Sclerosis, Breakthrough Study Finds
With the continuous quest in looking for the best solution for Multiple Sclerosis, a groundbreaking study claims that toxic brain cells are not toxic after all. Is the cure for the mysterious autoimmune disease close to being discovered? Here's what experts have to say
Parkinson's News: Opicapone Found To Offer Relief For Motor Problems
Parkinson's news report that an experimental drug called Opicapone can provide relief linked to motor problems to PD patients.
MORE IN ITECHPOST
Biometric Time and Attendance Tracking of Mobile Employees
Companies are challenged every day with keeping accurate track of their employees' time, attendance, and whereabouts. This is an essential part of managing a business enterprise, regardless of industry or the type of product or service being offered. Knowing how long it takes an employee to perform a task gives the company a basis for calculating the cost, price, and ultimately profit.
Artificial Intelligence Becomes Life-long Learner with New Framework
RESEARCH TRIANGLE PARK, N.C. (May 20, 2019) - A project of the U.S. Army has developed a new framework for deep neural networks that allow artificial intelligence systems to better learn new tasks while forgetting less of what they have learned regarding previous tasks.