Activated Macrophages: A New Cancer Treatment That Sheds Light To Possible Cure For Cancer, Is This The Solution To The Disease?
Long before, macrophages have been noted as a type of white blood cell that can engulf and destroy cancer cells. A new study led by Professor Matozaki Takashi, Associate Professor Murata Yoji, and Yanagita Tadahiko from Kobe University Department of Biochemistry and Molecular Biology, Division of Molecular and Cellular Signaling, have recently discovered that by using an antibody(2) for a particular protein found on macrophages, the macrophage is activated, and cancer cells are effectively eliminated. Thus, experts believe that the study findings could potentially be used to the development of new cancer treatments.
A Study On Activated Macrophages
According to reports revealed by Science Daily, since the emergence of cancer being one of the deadliest diseases in the world, attention has been drawn by the effectiveness of treatment that targets specific proteins that express on both cancer cells and healthy cells including immune system cells. However, the researchers have highly emphasized that some of the foreseen issues with the said treatment may include the emergence of cancer cells that are believed to be resistant to targeted drugs, and side effects which, in turn, differs from those for conventional anticancer drugs.
New Cancer Treatment That Sheds Light To Possible Cure For Cancer
Meanwhile, as reported by Kobe University Online, the findings obtained from Professor Matozaki's previous researches, the group has allegedly discovered that when the protein dubbed as SIRPα, which is expressed on the cell membrane of macrophages, is known to interact with the protein CD47 which is usually expressed on the cell membrane of engulfment targets such as cancer cells and senescent cells, the engulfment ability known as phagocytosis of the macrophages is inhibited.
Furthermore, the study findings clearly indicate that the antibodies used for SIRPα, which is an immune checkpoint molecule for macrophages related to the innate immune system function, can be used as a new cancer treatment. Ultimately, the researchers have highlighted that in the future, as well as analyzing the mechanism for the antitumor effect of anti-SIRPα antibodies in a more detailed perspective, while carefully assessing the safety of the treatment, anti-SIRPα antibodies do have the ability to be developed as anticancer drugs.
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Considering that it the World Cancer Awareness month, how important is it for people to have adequate knowledge in terms of fighting one of the long dreaded diseases in the world? Is the so-called ‘moonshot’ initiative the key in solving the problem caused by cancer? Find out what health professionals have to say
Two Cups Of Grapes A Day, Keeps Alzheimer's Away! Is Grapes The Key To Alzheimer's? New Study Suggests
Considering that there is no globally recognized cure to Alzheimer's disease, what's the truth behind the new claim that having two cups of grapes is the key in fighting Alzheimer's? What property of grapes is there that it can cure one of the most dreaded disease? Is it the solution that a lot of people have been waiting for? Here are the details
HIV Cure Update: Minister Of Health Claims Not Being Aware That Nigerian Professor Found An Alleged Cure For HIV; Good news or bad news?
A day after that the vice chancellor of Michael Okpara University made this claim that the answer to HIV has been found by a Nigerian professor, the Minister of Health is now denying that he has any knowledge regarding this matter. Here's what the Minister reveals.
Ancient Maya Civilization: Newly Discovered Artificial Plateau Challenges Traditional Archaeological Beliefs
Scientists have recently discovered new information about ancient Maya civilization breaking the traditional archaeological belief.
Blind People Can Now See the Shape of Different Letters with Brain Implant
A group of scientists from the Baylor College of Medicine located in Houston has recently developed a certain brain implant that actually allows both blind and sighted participants to "see" the shape of different letters!
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